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ELK Biotechnology

ES6711

RFWD3 Rabbit Polyclonal Antibody

RFWD3 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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RFWD3 Rabbit Polyclonal Antibody

Overview

Product name: RFWD3 rabbit pAb
Alternative Names: RFWD3; RNF201; E3 ubiquitin-protein ligase RFWD3; RING finger and WD repeat domain-containing protein 3; RING finger protein 201
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human RFWD3. AA range:374-423
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 85kD
GeneID（Human）: 55159
Human Swiss-Prot No: Q6PCD5
Cellular localization: Nucleus . Nucleus, PML body . Cytoplasm . In undamaged cells, found both in the cytoplasm and in the nucleus, partially associated with PML nuclear bodies (PubMed:21558276). In response to replication block, such as that caused by hydroxyurea treatment, or to DNA damage caused by ionizing radiations or doxorubicin, recruited to the nucleus, to stalled replication forks or to sites of DNA repair (PubMed:21504906, PubMed:28575657). This recruitment depends upon RPA2 (PubMed:21504906). .
Background: PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 3 WD repeats.,
Species Reactivity: Human;Rat;Mouse;
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