1
/
of
1
ELK Biotechnology
SKU:ES6703
PTG Rabbit Polyclonal Antibody
PTG Rabbit Polyclonal Antibody
Regular price
$248.00 USD
Regular price
Sale price
$248.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
PTG Rabbit Polyclonal Antibody
Overview
| Product name: | PTG rabbit pAb |
| Alternative Names: | PPP1R3C; PPP1R5; Protein phosphatase 1 regulatory subunit 3C; Protein phosphatase 1 regulatory subunit 5; PP1 subunit R5; Protein targeting to glycogen; PTG |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PPP1R3C. AA range:44-93 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 36kD |
| GeneID(Human): | 5507 |
| Human Swiss-Prot No: | Q9UQK1 |
| Cellular localization: | cytosol, |
| Background: | This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease. [provided by RefSeq, Sep 2016], |
| Species Reactivity: | Human;Monkey |
-
Immunohistochemical analysis of paraffin-embedded Human skeletal muscle. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-abs -
Western blot analysis of lysates from HepG2, HeLa, and COS7 cells, using PPP1R3C Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from HeLa cells using PPP1R3C antibody.
Share
