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ELK Biotechnology
SKU:ES6699
Epsin 3 Rabbit Polyclonal Antibody
Epsin 3 Rabbit Polyclonal Antibody
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$248.00 USD
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Epsin 3 Rabbit Polyclonal Antibody
Overview
| Product name: | Epsin 3 rabbit pAb |
| Alternative Names: | EPN3; Epsin-3; EPS-15-interacting protein 3 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human EPN3. AA range:401-450 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 68kD |
| GeneID(Human): | 55040 |
| Human Swiss-Prot No: | Q9H201 |
| Cellular localization: | Cytoplasm . Cytoplasm, perinuclear region . Cytoplasmic vesicle, clathrin-coated vesicle . Nucleus . Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus. |
| Background: | induction:In keratinocytes, by wounding or contact with collagen.,similarity:Belongs to the epsin family.,similarity:Contains 1 ENTH (epsin N-terminal homology) domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,subcellular location:Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.,tissue specificity:Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis., |
| Species Reactivity: | Human;Rat;Mouse; |
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Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using EPN3 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from K562 cells, using EPN3 Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from COLO205 cells using EPN3 antibody.
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