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ELK Biotechnology
SKU:ES6687
CLN6 Rabbit Polyclonal Antibody
CLN6 Rabbit Polyclonal Antibody
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$248.00 USD
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CLN6 Rabbit Polyclonal Antibody
Overview
| Product name: | CLN6 rabbit pAb |
| Alternative Names: | CLN6; Ceroid-lipofuscinosis neuronal protein 6; Protein CLN6 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CLN6. AA range:221-270 |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 40kD |
| GeneID(Human): | 54982 |
| Human Swiss-Prot No: | Q9NWW5 |
| Cellular localization: | Endoplasmic reticulum membrane ; Multi-pass membrane protein . Endoplasmic reticulum . |
| Background: | This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq, Oct 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using CLN6 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HeLa cells, using CLN6 Antibody. The lane on the right is blocked with the synthesized peptide.
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