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ELK Biotechnology

ES6673

MARCH5 Rabbit Polyclonal Antibody

MARCH5 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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MARCH5 Rabbit Polyclonal Antibody

Overview

Product name: MARCH5 rabbit pAb
Alternative Names: MARCH5; RNF153; E3 ubiquitin-protein ligase MARCH5; Membrane-associated RING finger protein 5; Membrane-associated RING-CH protein V; MARCH-V; Mitochondrial ubiquitin ligase; MITOL; RING finger protein 153
Applications: IF;WB;ELISA
Recommended Dilutions: WB 1:500-2000 Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MARCH5. AA range:21-70
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 37kD
GeneID（Human）: 54708
Human Swiss-Prot No: Q9NX47
Cellular localization: Mitochondrion outer membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Authors show that the protein can be detected in endoplasmic reticulum (PubMed:14722266). Authors (PubMed:16874301) show its presence only in mitochondria (PubMed:16874301). .
Background: MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008],
Species Reactivity: Human;Mouse;Rat
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