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ELK Biotechnology
SKU:ES6615
PC-PLD2 (phospho Tyr169) Rabbit Polyclonal Antibody
PC-PLD2 (phospho Tyr169) Rabbit Polyclonal Antibody
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PC-PLD2 (phospho Tyr169) Rabbit Polyclonal Antibody
Overview
| Product name: | PC-PLD2 (phospho Tyr169) rabbit pAb |
| Alternative Names: | PLD2; Phospholipase D2; PLD 2; hPLD2; Choline phosphatase 2; PLD1C; Phosphatidylcholine-hydrolyzing phospholipase D2 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PLD2 around the phosphorylation site of Tyr169. AA range:136-185 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 95kD |
| GeneID(Human): | 5338 |
| Human Swiss-Prot No: | O14939 |
| Cellular localization: | Cell membrane ; Lipid-anchor . |
| Background: | The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011], |
| Species Reactivity: | Human;Mouse;Rat |
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Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using PLD2 (Phospho-Tyr169) Antibody -
Immunohistochemistry analysis of paraffin-embedded human brain, using PLD2 (Phospho-Tyr169) Antibody. The picture on the right is blocked with the phospho peptide. -
Western blot analysis of lysates from Jurkat cells treated with TNF 20ng/ml 30', using PLD2 (Phospho-Tyr169) Antibody. The lane on the right is blocked with the phospho peptide.
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