1
/
of
1
ELK Biotechnology
SKU:ES6588
Pim-1 (phospho Tyr309) Rabbit Polyclonal Antibody
Pim-1 (phospho Tyr309) Rabbit Polyclonal Antibody
Regular price
$248.00 USD
Regular price
Sale price
$248.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
Pim-1 (phospho Tyr309) Rabbit Polyclonal Antibody
Overview
| Product name: | Pim-1 (phospho Tyr309) rabbit pAb |
| Alternative Names: | PIM1; Serine/threonine-protein kinase pim-1 |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Pim-1 around the phosphorylation site of Tyr309. AA range:281-330 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 45kD |
| GeneID（Human）: | 5292 |
| Human Swiss-Prot No: | P11309 |
| Cellular localization: | [Isoform 1]: Cytoplasm. Nucleus.; [Isoform 2]: Cell membrane. |
| Background: | The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011], |
| Species Reactivity: | Human;Mouse;Rat |
Share
