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ELK Biotechnology

ES6524

PDE4B/C/D (phospho Ser133/119/190) Rabbit Polyclonal Antibody

PDE4B/C/D (phospho Ser133/119/190) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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PDE4B/C/D (phospho Ser133/119/190) Rabbit Polyclonal Antibody

Overview

Product name: PDE4B/C/D (phospho Ser133/119/190) rabbit pAb
Alternative Names: PDE4B; DPDE4; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4B; DPDE4; PDE32; PDE4C; DPDE1; cAMP-specific 3',5'-cyclic phosphodiesterase 4C; DPDE1; PDE21; PDE4D; DPDE3; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; DPDE3; PDE43
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human PDE4D around the phosphorylation site of Ser190/53. AA range:156-205
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 76kD
GeneID（Human）: 5144
Human Swiss-Prot No: Q07343/Q08493/Q08499
Cellular localization: [Isoform PDE4B5]: Cytoplasm . Cell membrane .
Background: This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
Species Reactivity: Human;Mouse;Rat
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