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ELK Biotechnology

ES6501

LEF-1 (phospho Ser42) Rabbit Polyclonal Antibody

LEF-1 (phospho Ser42) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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LEF-1 (phospho Ser42) Rabbit Polyclonal Antibody

Overview

Product name: LEF-1 (phospho Ser42) rabbit pAb
Alternative Names: LEF1; Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human LEF-1 around the phosphorylation site of Ser42. AA range:8-57
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 55kD
GeneID（Human）: 51176
Human Swiss-Prot No: Q9UJU2
Cellular localization: Nucleus . Found in nuclear bodies upon PIASG binding. .
Background: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
Species Reactivity: Human;Mouse;Rat
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