1 1

ELK Biotechnology

ES6488

PCB Rabbit Polyclonal Antibody

PCB Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
Sale Sold out
Shipping calculated at checkout.
Size

PCB Rabbit Polyclonal Antibody

Overview

Product name: PCB rabbit pAb
Alternative Names: PC; Pyruvate carboxylase; mitochondrial; Pyruvic carboxylase; PCB
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human PC. AA range:357-406
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 120kD
GeneID（Human）: 5091
Human Swiss-Prot No: P11498
Cellular localization: Mitochondrion matrix .
Background: This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
View full details