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ELK Biotechnology

ES6445

KOR-1 Rabbit Polyclonal Antibody

KOR-1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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KOR-1 Rabbit Polyclonal Antibody

Overview

Product name: KOR-1 rabbit pAb
Alternative Names: OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human OPRK1. AA range:321-370
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 48kD
GeneID（Human）: 4986
Human Swiss-Prot No: P41145
Cellular localization: Cell membrane ; Multi-pass membrane protein .
Background: This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jan 2016],
Species Reactivity: Human;Mouse;Rat;Monkey
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