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ELK Biotechnology
SKU:ES6404
CNOT2 Rabbit Polyclonal Antibody
CNOT2 Rabbit Polyclonal Antibody
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$248.00 USD
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CNOT2 Rabbit Polyclonal Antibody
Overview
| Product name: | CNOT2 rabbit pAb |
| Alternative Names: | CNOT2; CDC36; NOT2; HSPC131; MSTP046; CCR4-NOT transcription complex subunit 2; CCR4-associated factor 2 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CNOT2. AA range:67-116 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 46kD |
| GeneID(Human): | 4848 |
| Human Swiss-Prot No: | Q9NZN8 |
| Cellular localization: | Cytoplasm . Nucleus . |
| Background: | CCR4-NOT transcription complex subunit 2(CNOT2) Homo sapiens This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010], |
| Species Reactivity: | Human;Mouse;Rat |
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Western blot analysis of lysates from HepG2 cells, treated with starved 24h, using CNOT2 Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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