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ELK Biotechnology

ES6362

Na+/K+-ATPase α2 Rabbit Polyclonal Antibody

Na+/K+-ATPase α2 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Na+/K+-ATPase α2 Rabbit Polyclonal Antibody

Overview

Product name: Na+/K+-ATPase α2 rabbit pAb
Alternative Names: ATP1A2; KIAA0778; Sodium/potassium-transporting ATPase subunit alpha-2; Na(+)/K(+) ATPase alpha-2 subunit; Sodium pump subunit alpha-2
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human ATP1A2. AA range:971-1020
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 112kD
GeneID（Human）: 477
Human Swiss-Prot No: P50993
Cellular localization: Membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .
Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008],
Species Reactivity: Human;Mouse;Rat;Monkey
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