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ELK Biotechnology

ES6360

Neuro D (phospho Ser274) Rabbit Polyclonal Antibody

Neuro D (phospho Ser274) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Neuro D (phospho Ser274) Rabbit Polyclonal Antibody

Overview

Product name: Neuro D (phospho Ser274) rabbit pAb
Alternative Names: NEUROD1; BHLHA3; NEUROD; Neurogenic differentiation factor 1; NeuroD; NeuroD1; Class A basic helix-loop-helix protein 3; bHLHa3
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human Neuro D around the phosphorylation site of Ser274. AA range:240-289
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 36kD
GeneID（Human）: 4760
Human Swiss-Prot No: Q13562
Cellular localization: Cytoplasm . Nucleus . In pancreatic islet cells, shuttles to the nucleus in response to glucose stimulation (By similarity). Colocalizes with NR0B2 in the nucleus. .
Background: This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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