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ELK Biotechnology

ES6285

Ron (phospho Ser1394) Rabbit Polyclonal Antibody

Ron (phospho Ser1394) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Ron (phospho Ser1394) Rabbit Polyclonal Antibody

Overview

Product name: Ron (phospho Ser1394) rabbit pAb
Alternative Names: MST1R; PTK8; RON; Macrophage-stimulating protein receptor; MSP receptor; CDw136; Protein-tyrosine kinase 8; p185-Ron; CD antigen CD136
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human CD136/RON around the phosphorylation site of Ser1394. AA range:1351-1400
Storage: -20°C/1 year
Storage: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 152kD
GeneID（Human）: 4486
Human Swiss-Prot No: Q04912
Cellular localization: Membrane; Single-pass type I membrane protein.
Background: This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016],
Species Reactivity: Human;Mouse
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