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ELK Biotechnology
SKU:ES6284
Moesin/Ezrin/Radixin Rabbit Polyclonal Antibody
Moesin/Ezrin/Radixin Rabbit Polyclonal Antibody
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Moesin/Ezrin/Radixin Rabbit Polyclonal Antibody
Overview
| Product name: | Moesin/Ezrin/Radixin rabbit pAb |
| Alternative Names: | MSN; Moesin; Membrane-organizing extension spike protein; RDX; Radixin; EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Moesin/Ezrin/Radixin. AA range:524-573 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 67kD |
| GeneID(Human): | 4478/5962 |
| Human Swiss-Prot No: | P26038/P35241/P15311 |
| Cellular localization: | Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Apical cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, microvillus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, microvillus . Phosphorylated form is enriched in microvilli-like structures at apical membrane. Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment (By similarity). Localizes at the uropods of T lymphoblasts. . |
| Background: | Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of 3T3 cells using Moesin/Ezrin/Radixin Polyclonal Antibody diluted at 1:2000 -
Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using Moesin/Ezrin/Radixin Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from NIH/3T3 cells, using Moesin/Ezrin/Radixin Antibody. The lane on the right is blocked with the synthesized peptide.
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