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ELK Biotechnology

SKU:ES6260

MMP-8 Rabbit Polyclonal Antibody

MMP-8 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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MMP-8 Rabbit Polyclonal Antibody

Overview

Product name: MMP-8 rabbit pAb
Alternative Names: MMP8; CLG1; Neutrophil collagenase; Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CL
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MMP-8. AA range:418-467
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 55kD
GeneID(Human): 4317
Human Swiss-Prot No: P22894
Cellular localization: Cytoplasmic granule. Secreted, extracellular space, extracellular matrix . Stored in intracellular granules.
Background: matrix metallopeptidase 8(MMP8) Homo sapiens This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
Species Reactivity: Human;Mouse;Rat
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