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ELK Biotechnology

ES6245

MITF (phospho Ser180) Rabbit Polyclonal Antibody

MITF (phospho Ser180) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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MITF (phospho Ser180) Rabbit Polyclonal Antibody

Overview

Product name: MITF (phospho Ser180) rabbit pAb
Alternative Names: MITF; BHLHE32; Microphthalmia-associated transcription factor; Class E basic helix-loop-helix protein 32; bHLHe32
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MITF around the phosphorylation site of Ser180/73. AA range:151-200
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 52kD
GeneID（Human）: 4286
Human Swiss-Prot No: O75030
Cellular localization: Nucleus . Cytoplasm . Found exclusively in the nucleus upon phosphorylation. .
Background: This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Monkey
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