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ELK Biotechnology

SKU:ES6215

PRDM3 Rabbit Polyclonal Antibody

PRDM3 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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PRDM3 Rabbit Polyclonal Antibody

Overview

Product name: PRDM3 rabbit pAb
Alternative Names: MECOM; MDS1; MDS1 and EVI1 complex locus protein MDS1; Myelodysplasia syndrome 1 protein; Myelodysplasia syndrome-associated protein 1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MECOM. AA range:1-50
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 18kD
GeneID(Human): 4197
Human Swiss-Prot No: Q13465
Cellular localization: histone deacetylase complex,nucleus,nucleoplasm,cytoplasm,Golgi apparatus,cytosol,aggresome,nuclear speck,intracellular membrane-bounded organelle,
Background: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],
Species Reactivity: Human;Rat;Mouse;
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