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ELK Biotechnology
SKU:ES6215
PRDM3 Rabbit Polyclonal Antibody
PRDM3 Rabbit Polyclonal Antibody
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$248.00 USD
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PRDM3 Rabbit Polyclonal Antibody
Overview
| Product name: | PRDM3 rabbit pAb |
| Alternative Names: | MECOM; MDS1; MDS1 and EVI1 complex locus protein MDS1; Myelodysplasia syndrome 1 protein; Myelodysplasia syndrome-associated protein 1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MECOM. AA range:1-50 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 18kD |
| GeneID(Human): | 4197 |
| Human Swiss-Prot No: | Q13465 |
| Cellular localization: | histone deacetylase complex,nucleus,nucleoplasm,cytoplasm,Golgi apparatus,cytosol,aggresome,nuclear speck,intracellular membrane-bounded organelle, |
| Background: | The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of A549 cells using PRDM3 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Western blot analysis of lysates from A549 cells, using Myelodysplasia Syndrome 1 Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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