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ELK Biotechnology

SKU:ES6205

Mcl-1 (phospho Ser159) Rabbit Polyclonal Antibody

Mcl-1 (phospho Ser159) Rabbit Polyclonal Antibody

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Mcl-1 (phospho Ser159) Rabbit Polyclonal Antibody

Overview

Product name: Mcl-1 (phospho Ser159) rabbit pAb
Alternative Names: MCL1; BCL2L3; Induced myeloid leukemia cell differentiation protein Mcl-1; Bcl-2-like protein 3; Bcl2-L-3; Bcl-2-related protein EAT/mcl1; mcl1/EAT
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human MCL1 around the phosphorylation site of Ser159. AA range:125-174
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: About 40kd in human,39kd in mouse and rat
GeneID(Human): 4170
Human Swiss-Prot No: Q07820
Cellular localization: Membrane ; Single-pass membrane protein . Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Cytoplasmic, associated with mitochondria.
Background: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010],
Species Reactivity: Human;Mouse
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