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ELK Biotechnology

SKU:ES6151

MARCKS Rabbit Polyclonal Antibody

MARCKS Rabbit Polyclonal Antibody

Regular price $248.00 USD
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MARCKS Rabbit Polyclonal Antibody

Overview

Product name: MARCKS rabbit pAb
Alternative Names: MARCKS; MACS; PRKCSL; Myristoylated alanine-rich C-kinase substrate; MARCKS; Protein kinase C substrate; 80 kDa protein, light chain; 80K-L protein; PKCSL
Applications: WB;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MARCKS. AA range:126-175
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 31kD
GeneID(Human): 4082
Human Swiss-Prot No: P29966
Cellular localization: Cytoplasm, cytoskeleton . Membrane ; Lipid-anchor .
Background: The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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