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ELK Biotechnology

SKU:ES6150

MARCKS (phospho Ser163) Rabbit Polyclonal Antibody

MARCKS (phospho Ser163) Rabbit Polyclonal Antibody

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MARCKS (phospho Ser163) Rabbit Polyclonal Antibody

Overview

Product name: MARCKS (phospho Ser163) rabbit pAb
Alternative Names: MARCKS; MACS; PRKCSL; Myristoylated alanine-rich C-kinase substrate; MARCKS; Protein kinase C substrate; 80 kDa protein, light chain; 80K-L protein; PKCSL
Applications: IHC;IF;ELISA
Recommended Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MARCKS around the phosphorylation site of Ser163. AA range:136-185
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID(Human): 4082
Human Swiss-Prot No: P29966
Cellular localization: Cytoplasm, cytoskeleton . Membrane ; Lipid-anchor .
Background: The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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