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ELK Biotechnology
SKU:ES6150
MARCKS (phospho Ser163) Rabbit Polyclonal Antibody
MARCKS (phospho Ser163) Rabbit Polyclonal Antibody
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MARCKS (phospho Ser163) Rabbit Polyclonal Antibody
Overview
| Product name: | MARCKS (phospho Ser163) rabbit pAb |
| Alternative Names: | MARCKS; MACS; PRKCSL; Myristoylated alanine-rich C-kinase substrate; MARCKS; Protein kinase C substrate; 80 kDa protein, light chain; 80K-L protein; PKCSL |
| Applications: | IHC;IF;ELISA |
| Recommended Dilutions: | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MARCKS around the phosphorylation site of Ser163. AA range:136-185 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| GeneID(Human): | 4082 |
| Human Swiss-Prot No: | P29966 |
| Cellular localization: | Cytoplasm, cytoskeleton . Membrane ; Lipid-anchor . |
| Background: | The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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