1
/
of
1
ELK Biotechnology
SKU:ES6149
MARCKS (phospho Ser158) Rabbit Polyclonal Antibody
MARCKS (phospho Ser158) Rabbit Polyclonal Antibody
Regular price
$248.00 USD
Regular price
Sale price
$248.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
MARCKS (phospho Ser158) Rabbit Polyclonal Antibody
Overview
| Product name: | MARCKS (phospho Ser159) rabbit pAb |
| Alternative Names: | MARCKS; MACS; PRKCSL; Myristoylated alanine-rich C-kinase substrate; MARCKS; Protein kinase C substrate; 80 kDa protein, light chain; 80K-L protein; PKCSL |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MARCKS around the phosphorylation site of Ser158. AA range:126-175 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 35kD |
| GeneID(Human): | 4082 |
| Human Swiss-Prot No: | P29966 |
| Cellular localization: | Cytoplasm, cytoskeleton . Membrane ; Lipid-anchor . |
| Background: | The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
-
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using MARCKS (Phospho-Ser158) Antibody -
Western blot analysis of lysates from K562 cells treated with EGF 200ng/ml 30', using MARCKS (Phospho-Ser158) Antibody. The lane on the right is blocked with the phospho peptide.
Share
