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ELK Biotechnology
SKU:ES6145
Arrestin-C Rabbit Polyclonal Antibody
Arrestin-C Rabbit Polyclonal Antibody
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Arrestin-C Rabbit Polyclonal Antibody
Overview
| Product name: | Arrestin-C rabbit pAb |
| Alternative Names: | ARR3; ARRX; CAR; Arrestin-C; Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human ARRC. AA range:339-388 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 40kD |
| GeneID(Human): | 407 |
| Human Swiss-Prot No: | P36575 |
| Cellular localization: | Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment . |
| Background: | The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western blot analysis of lysates from LOVO cells, using ARRC Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
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