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ELK Biotechnology
SKU:ES6138
LRP3 Rabbit Polyclonal Antibody
LRP3 Rabbit Polyclonal Antibody
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$248.00 USD
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LRP3 Rabbit Polyclonal Antibody
Overview
| Product name: | LRP3 rabbit pAb |
| Alternative Names: | LRP3; Low-density lipoprotein receptor-related protein 3; LRP-3; 105 kDa low-density lipoprotein receptor-related protein; hLRp105 |
| Applications: | WB;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human LRP3. AA range:17-66 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 80kD |
| GeneID(Human): | 4037 |
| Human Swiss-Prot No: | O75074 |
| Cellular localization: | Membrane ; Single-pass type I membrane protein . Membrane, coated pit . |
| Background: | function:Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.,similarity:Belongs to the LDLR family.,similarity:Contains 2 CUB domains.,similarity:Contains 4 LDL-receptor class A domains.,subunit:Binds GGA1 and GGA2.,tissue specificity:Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte., |
| Species Reactivity: | Human;Mouse;Rat |
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Western blot analysis of lysates from RAW264.7 cells, using LRP3 Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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