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ELK Biotechnology
SKU:ES6076
Rho G Rabbit Polyclonal Antibody
Rho G Rabbit Polyclonal Antibody
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$248.00 USD
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Rho G Rabbit Polyclonal Antibody
Overview
| Product name: | Rho G rabbit pAb |
| Alternative Names: | RHOG; ARHG; Rho-related GTP-binding protein RhoG |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human RHOG. AA range:97-146 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 23kD |
| GeneID(Human): | 391 |
| Human Swiss-Prot No: | P84095 |
| Cellular localization: | Cell membrane ; Lipid-anchor ; Cytoplasmic side . |
| Background: | This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011], |
| Species Reactivity: | Human;Mouse;Rat |
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Western blot analysis of lysates from Jurkat cells, using RHOG Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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