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ELK Biotechnology

ES5967

eIF4B (phospho Ser422) Rabbit Polyclonal Antibody

eIF4B (phospho Ser422) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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eIF4B (phospho Ser422) Rabbit Polyclonal Antibody

Overview

Product name: eIF4B (phospho Ser422) rabbit pAb
Alternative Names: EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human eIF4B around the phosphorylation site of Ser422. AA range:388-437
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 80kD
GeneID（Human）: 3716
Human Swiss-Prot No: P23588
Cellular localization: cytosol,polysome,eukaryotic translation initiation factor 4F complex,dendrite,neuronal cell body,
Background: function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit.,
Species Reactivity: Human;Mouse
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