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ELK Biotechnology
SKU:ES5956
Integrin β3 (phospho Tyr773) Rabbit Polyclonal Antibody
Integrin β3 (phospho Tyr773) Rabbit Polyclonal Antibody
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Integrin β3 (phospho Tyr773) Rabbit Polyclonal Antibody
Overview
| Product name: | Integrin β3 (phospho Tyr773) rabbit pAb |
| Alternative Names: | ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Integrin beta3 around the phosphorylation site of Tyr773. AA range:739-788 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 130kD |
| GeneID(Human): | 3690 |
| Human Swiss-Prot No: | P05106 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane . Cell junction, focal adhesion . Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein . Cell junction, synapse . |
| Background: | The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Integrin beta3 (Phospho-Tyr773) Antibody. The picture on the right is blocked with the phospho peptide. -
Western blot analysis of lysates from HL-60 cells treated with H2O2, using Integrin beta3 (Phospho-Tyr773) Antibody. The lane on the right is blocked with the phospho peptide.
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