IGF-IR Rabbit Polyclonal Antibody

Name: IGF-IR Rabbit Polyclonal Antibody
Brand: ELK Biotechnology
SKU: ES5849
Price: 248.0 USD
Availability: InStock

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IGF-IR Rabbit Polyclonal Antibody

Product name:	IGF-IR rabbit pAb
Alternative Names:	IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
Applications:	WB;IHC;IF;ELISA
Recommended Dilutions:	IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human IGF1R. AA range:1131-1180
Storage:	Rabbit
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	pro: 155kD, recetor beta: 95kD
GeneID（Human）:	3480
Human Swiss-Prot No:	P08069
Cellular localization:	Cell membrane ; Single-pass type I membrane protein .
Background:	This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
Species Reactivity:	Human;Mouse;Rat

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