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ELK Biotechnology
SKU:ES5822
Synaptotagmin X Rabbit Polyclonal Antibody
Synaptotagmin X Rabbit Polyclonal Antibody
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Synaptotagmin X Rabbit Polyclonal Antibody
Overview
| Product name: | Synaptotagmin X rabbit pAb |
| Alternative Names: | SYT10; Synaptotagmin-10; Synaptotagmin X; SytX |
| Applications: | WB;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: | Synthesized peptide derived from Synaptotagmin X . at AA range: 380-460 |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 55kD |
| GeneID(Human): | 341359 |
| Human Swiss-Prot No: | Q6XYQ8 |
| Cellular localization: | Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus. . |
| Background: | cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney., |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of 293 cells using Synaptotagmin X Polyclonal Antibody -
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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