HC-II Rabbit Polyclonal Antibody

Name: HC-II Rabbit Polyclonal Antibody
Brand: ELK Biotechnology
SKU: ES5718
Price: 248.0 USD
Availability: InStock

$248.00 USD

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HC-II Rabbit Polyclonal Antibody

Product name:	HC-II rabbit pAb
Alternative Names:	SERPIND1; HCF2; Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; HLS2; Serpin D1
Applications:	WB;IHC;IF;ELISA
Recommended Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human Heparin Cofactor II. AA range:41-90
Storage:	Rabbit
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	60kD
GeneID（Human）:	3053
Human Swiss-Prot No:	P05546
Cellular localization:	extracellular region,extracellular space,extracellular exosome,
Background:	This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015],
Species Reactivity:	Human;Mouse;Rat

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