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ELK Biotechnology
SKU:ES5709
Granzyme A Rabbit Polyclonal Antibody
Granzyme A Rabbit Polyclonal Antibody
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Granzyme A Rabbit Polyclonal Antibody
Overview
| Product name: | Granzyme A rabbit pAb |
| Alternative Names: | GZMA; CTLA3; HFSP; Granzyme A; CTL tryptase; Cytotoxic T-lymphocyte proteinase 1; Fragmentin-1; Granzyme-1; Hanukkah factor; H factor; HF |
| Applications: | IHC;IF;ELISA |
| Recommended Dilutions: | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human GRAA. AA range:61-110 |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| GeneID(Human): | 3001 |
| Human Swiss-Prot No: | P12544 |
| Cellular localization: | [Isoform alpha]: Secreted . Cytoplasmic granule . Delivered into the target cell by perforin. . |
| Background: | Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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Immunofluorescence analysis of HepG2 cells, using GRAA Antibody. The picture on the right is blocked with the synthesized peptide. -
Immunohistochemistry analysis of paraffin-embedded human heart tissue, using GRAA Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from HUVECcells using MUTYH antibody.
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