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ELK Biotechnology
SKU:ES5708
Fibulin-4 Rabbit Polyclonal Antibody
Fibulin-4 Rabbit Polyclonal Antibody
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Fibulin-4 Rabbit Polyclonal Antibody
Overview
| Product name: | Fibulin-4 rabbit pAb |
| Alternative Names: | EFEMP2; FBLN4; EGF-containing fibulin-like extracellular matrix protein 2; Fibulin-4; FIBL-4; Protein UPH1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human EFEMP2. AA range:91-140 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 50kD |
| GeneID(Human): | 30008 |
| Human Swiss-Prot No: | O95967 |
| Cellular localization: | Secreted, extracellular space, extracellular matrix . Secreted, extracellular space, extracellular matrix, basement membrane . Localizes on the microfibrils surrounding ELN cores. . |
| Background: | A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011], |
| Species Reactivity: | Human;Rat;Mouse; |
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Immunofluorescence analysis of A549 cells, using EFEMP2 Antibody. The picture on the right is blocked with the synthesized peptide. -
Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using EFEMP2 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from K562 and NIH/3T3 cells, using EFEMP2 Antibody. The lane on the right is blocked with the synthesized peptide.
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