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ELK Biotechnology
SKU:ES5689
TFII-I (phospho Tyr248) Rabbit Polyclonal Antibody
TFII-I (phospho Tyr248) Rabbit Polyclonal Antibody
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$248.00 USD
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TFII-I (phospho Tyr248) Rabbit Polyclonal Antibody
Overview
| Product name: | TFII-I (phospho Tyr248) rabbit pAb |
| Alternative Names: | GTF2I; BAP135; WBSCR6; General transcription factor II-I; GTFII-I; TFII-I; Bruton tyrosine kinase-associated protein 135; BAP-135; BTK-associated protein 135; SRF-Phox1-interacting protein; SPIN; Williams-Beuren syndrome chromosomal region |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human TFII-I around the phosphorylation site of Tyr248. AA range:214-263 |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 115kD |
| GeneID(Human): | 2969 |
| Human Swiss-Prot No: | P78347 |
| Cellular localization: | Cytoplasm . Nucleus . Colocalizes with BTK in the cytoplasm. |
| Background: | general transcription factor IIi(GTF2I) Homo sapiens This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2013], |
| Species Reactivity: | Human;Mouse;Rat |
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Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using TFII-I (Phospho-Tyr248) Antibody -
Western blot analysis of lysates from LOVO cells, using TFII-I (Phospho-Tyr248) Antibody. The lane on the right is blocked with the phospho peptide.
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