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ELK Biotechnology
SKU:ES5656
NMDAε2 (phospho Tyr1336) Rabbit Polyclonal Antibody
NMDAε2 (phospho Tyr1336) Rabbit Polyclonal Antibody
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NMDAε2 (phospho Tyr1336) Rabbit Polyclonal Antibody
Overview
| Product name: | NMDAε2 (phospho Tyr1336) rabbit pAb |
| Alternative Names: | GRIN2B; NMDAR2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B; NMDAR2B; NR2B; N-methyl-D-aspartate receptor subunit 3; NR3; hNR3 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NMDAR2B around the phosphorylation site of Tyr1336. AA range:1302-1351 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 150kD |
| GeneID(Human): | 2904 |
| Human Swiss-Prot No: | Q13224 |
| Cellular localization: | Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Late endosome . Lysosome . Cytoplasm, cytoskeleton . Co-localizes with the motor protein KIF17 along microtubules. . |
| Background: | N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of 293T-UV cells using Phospho-NMDAε2 (Y1336) Polyclonal Antibody diluted at 1:500 -
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using NMDAR2B (Phospho-Tyr1336) Antibody -
Immunohistochemistry analysis of paraffin-embedded human brain, using NMDAR2B (Phospho-Tyr1336) Antibody. The picture on the right is blocked with the phospho peptide. -
Western blot analysis of lysates from Jurkat cells treated with TNF 20ng/ml 30', using NMDAR2B (Phospho-Tyr1336) Antibody. The lane on the right is blocked with the phospho peptide.
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