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ELK Biotechnology

SKU:ES5573

PR48 Rabbit Polyclonal Antibody

PR48 Rabbit Polyclonal Antibody

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PR48 Rabbit Polyclonal Antibody

Overview

Product name: PR48 rabbit pAb
Alternative Names: PPP2R3B; PPP2R3L; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta; PP2A subunit B isoform PR48; Protein phosphatase 2A 48 kDa regulatory subunit
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human PPP2R3B. AA range:364-413
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 70kD
GeneID(Human): 28227
Human Swiss-Prot No: Q9Y5P8
Cellular localization: Nucleus .
Background: Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. [provided by RefSeq, Apr 2010],
Species Reactivity: Human;Rat;Mouse;
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