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ELK Biotechnology

ES5550

Pdcd-4 (phospho Ser457) Rabbit Polyclonal Antibody

Pdcd-4 (phospho Ser457) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Pdcd-4 (phospho Ser457) Rabbit Polyclonal Antibody

Overview

Product name: Pdcd-4 (phospho Ser457) rabbit pAb
Alternative Names: PDCD4; H731; Programmed cell death protein 4; Neoplastic transformation inhibitor protein; Nuclear antigen H731-like; Protein 197/15a
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human PDCD4 around the phosphorylation site of Ser457. AA range:420-469
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 51kD
GeneID（Human）: 27250
Human Swiss-Prot No: Q53EL6
Cellular localization: Nucleus . Cytoplasm . Shuttles between the nucleus and cytoplasm (By similarity). Predominantly nuclear under normal growth conditions, and when phosphorylated at Ser-457 (PubMed:16357133). .
Background: This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010],
Species Reactivity: Human;Mouse;Rat
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