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ELK Biotechnology
SKU:ES5549
Pdcd-4 (phospho Ser67) Rabbit Polyclonal Antibody
Pdcd-4 (phospho Ser67) Rabbit Polyclonal Antibody
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Pdcd-4 (phospho Ser67) Rabbit Polyclonal Antibody
Overview
| Product name: | Pdcd-4 (phospho Ser67) rabbit pAb |
| Alternative Names: | PDCD4; H731; Programmed cell death protein 4; Neoplastic transformation inhibitor protein; Nuclear antigen H731-like; Protein 197/15a |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PDCD4 around the phosphorylation site of Ser67. AA range:33-82 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 56kD |
| GeneID(Human): | 27250 |
| Human Swiss-Prot No: | Q53EL6 |
| Cellular localization: | Nucleus . Cytoplasm . Shuttles between the nucleus and cytoplasm (By similarity). Predominantly nuclear under normal growth conditions, and when phosphorylated at Ser-457 (PubMed:16357133). . |
| Background: | This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010], |
| Species Reactivity: | Human;Mouse;Rat;Monkey |
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Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by i -
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by i -
Western blot analysis of lysates from HUVEC cells, K562 cells and COS-7 cells, using PDCD4 (Phospho-Ser67) Antibody. The lane on the right is blocked with the phospho peptide.
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