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ELK Biotechnology
SKU:ES5488
ARF GAP3 Rabbit Polyclonal Antibody
ARF GAP3 Rabbit Polyclonal Antibody
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$248.00 USD
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ARF GAP3 Rabbit Polyclonal Antibody
Overview
| Product name: | ARF GAP3 rabbit pAb |
| Alternative Names: | ARFGAP3; ARFGAP1; ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3 |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | Synthesized peptide derived from ARF GAP3 . at AA range: 280-360 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 60kD |
| GeneID（Human）: | 26286 |
| Human Swiss-Prot No: | Q9NP61 |
| Cellular localization: | Cytoplasm . Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment. |
| Background: | The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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