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ELK Biotechnology
SKU:ES5468
NOC2L Rabbit Polyclonal Antibody
NOC2L Rabbit Polyclonal Antibody
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$248.00 USD
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NOC2L Rabbit Polyclonal Antibody
Overview
| Product name: | NOC2L rabbit pAb |
| Alternative Names: | NOC2L; NIR; Nucleolar complex protein 2 homolog; Protein NOC2 homolog; NOC2-like protein; Novel INHAT repressor |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NOC2L. AA range:602-651 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 85kD |
| GeneID（Human）: | 26155 |
| Human Swiss-Prot No: | Q9Y3T9 |
| Cellular localization: | Nucleus, nucleoplasm. Nucleus, nucleolus. Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin-D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis. |
| Background: | NOC2 like nucleolar associated transcriptional repressor(NOC2L) Homo sapiens Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]).[supplied by OMIM, Mar 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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