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ELK Biotechnology

ES5432

GABAA Rδ Rabbit Polyclonal Antibody

GABAA Rδ Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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GABAA Rδ Rabbit Polyclonal Antibody

Overview

Product name: GABAA Rδ rabbit pAb
Alternative Names: GABRD; Gamma-aminobutyric acid receptor subunit delta; GABA(A) receptor subunit delta
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human GABRD. AA range:141-190
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 51kD
GeneID（Human）: 2563
Human Swiss-Prot No: O14764
Cellular localization: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Background: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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