Ku-70 (phospho Ser5) Rabbit Polyclonal Antibody

Name: Ku-70 (phospho Ser5) Rabbit Polyclonal Antibody
Brand: ELK Biotechnology
SKU: ES5420
Price: 248.0 USD
Availability: InStock

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Ku-70 (phospho Ser5) Rabbit Polyclonal Antibody

Product name:	Ku-70 (phospho Ser5) rabbit pAb
Alternative Names:	XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-
Applications:	WB;IHC;IF;ELISA
Recommended Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human Ku70 around the phosphorylation site of Ser5. AA range:1-50
Storage:	Rabbit
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	70kD
GeneID（Human）:	2547
Human Swiss-Prot No:	P12956
Cellular localization:	Nucleus . Chromosome .
Background:	The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008],
Species Reactivity:	Human;Mouse

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