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ELK Biotechnology
SKU:ES5417
Frizzled-2 Rabbit Polyclonal Antibody
Frizzled-2 Rabbit Polyclonal Antibody
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Frizzled-2 Rabbit Polyclonal Antibody
Overview
| Product name: | Frizzled-2 rabbit pAb |
| Alternative Names: | FZD2; Frizzled-2; Fz-2; hFz2; FzE2 |
| Applications: | WB;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human FZD2. AA range:201-250 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 55kD |
| GeneID(Human): | 2535 |
| Human Swiss-Prot No: | Q14332 |
| Cellular localization: | Membrane; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein . |
| Background: | frizzled class receptor 2(FZD2) Homo sapiens This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. [provided by RefSeq, Dec 2010], |
| Species Reactivity: | Human;Mouse;Rat |
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Immunofluorescence analysis of MCF7 cells, using FZD2 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HeLa cells, using FZD2 Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from HepG2 cells using FZD2 antibody.
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