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ELK Biotechnology

ES5379

CARKL Rabbit Polyclonal Antibody

CARKL Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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CARKL Rabbit Polyclonal Antibody

Overview

Product name: CARKL rabbit pAb
Alternative Names: SHPK; CARKL; Sedoheptulokinase; SHK; Carbohydrate kinase-like protein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CARKL. AA range:31-80
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 55kD
GeneID（Human）: 23729
Human Swiss-Prot No: Q9UHJ6
Cellular localization: Cytoplasm .
Background: sedoheptulokinase(SHPK) Homo sapiens The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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