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ELK Biotechnology

ES5372

NTR2 Rabbit Polyclonal Antibody

NTR2 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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NTR2 Rabbit Polyclonal Antibody

Overview

Product name: NTR2 rabbit pAb
Alternative Names: NTSR2; Neurotensin receptor type 2; NT-R-2; NTR2; Levocabastine-sensitive neurotensin receptor
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human NTR2. AA range:151-200
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 45kD
GeneID（Human）: 23620
Human Swiss-Prot No: O95665
Cellular localization: Cell membrane; Multi-pass membrane protein.
Background: The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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