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ELK Biotechnology
SKU:ES5356
JIP-2 Rabbit Polyclonal Antibody
JIP-2 Rabbit Polyclonal Antibody
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JIP-2 Rabbit Polyclonal Antibody
Overview
| Product name: | JIP-2 rabbit pAb |
| Alternative Names: | MAPK8IP2; IB2; JIP2; PRKM8IPL; C-Jun-amino-terminal kinase-interacting protein 2; JIP-2; JNK-interacting protein 2; Islet-brain-2; IB-2; JNK MAP kinase scaffold protein 2; Mitogen-activated protein kinase 8-interacting protein 2 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human JIP2. AA range:581-630 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 87kD |
| GeneID(Human): | 23542 |
| Human Swiss-Prot No: | Q13387 |
| Cellular localization: | Cytoplasm . Accumulates in cell surface projections. . |
| Background: | The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. [provided by RefSeq, Feb 2014], |
| Species Reactivity: | Human;Mouse;Rat |
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Immunofluorescence analysis of HeLa cells, using JIP2 Antibody. The picture on the right is blocked with the synthesized peptide. -
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using JIP2 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from mouse brain, using JIP2 Antibody. The lane on the right is blocked with the synthesized peptide.
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