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ELK Biotechnology

SKU:ES5333

LARG Rabbit Polyclonal Antibody

LARG Rabbit Polyclonal Antibody

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LARG Rabbit Polyclonal Antibody

Overview

Product name: LARG rabbit pAb
Alternative Names: ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 173kD
GeneID(Human): 23365
Human Swiss-Prot No: Q9NZN5
Cellular localization: Cytoplasm . Membrane . Translocated to the membrane upon stimulation. .
Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
Species Reactivity: Human;Mouse;Rat
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