1
/
of
1
ELK Biotechnology
SKU:ES5333
LARG Rabbit Polyclonal Antibody
LARG Rabbit Polyclonal Antibody
Regular price
$248.00 USD
Regular price
Sale price
$248.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
LARG Rabbit Polyclonal Antibody
Overview
| Product name: | LARG rabbit pAb |
| Alternative Names: | ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF |
| Applications: | WB;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 173kD |
| GeneID(Human): | 23365 |
| Human Swiss-Prot No: | Q9NZN5 |
| Cellular localization: | Cytoplasm . Membrane . Translocated to the membrane upon stimulation. . |
| Background: | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014], |
| Species Reactivity: | Human;Mouse;Rat |
-
Western Blot analysis of RAW264.7 cells using LARG Polyclonal Antibody -
Western blot analysis of lysates from RAW264.7 cells, using ARHGEF12 Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from HUVECcells using ARHGEF12 antibody. -
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
Share
