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ELK Biotechnology
SKU:ES5316
Glucosidase IIα Rabbit Polyclonal Antibody
Glucosidase IIα Rabbit Polyclonal Antibody
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$248.00 USD
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Glucosidase IIα Rabbit Polyclonal Antibody
Overview
| Product name: | Glucosidase IIα rabbit pAb |
| Alternative Names: | GANAB; G2AN; KIAA0088; Neutral alpha-glucosidase AB; Alpha-glucosidase 2; Glucosidase II subunit alpha |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human GANAB. AA range:242-291 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 107kD |
| GeneID(Human): | 23193 |
| Human Swiss-Prot No: | Q14697 |
| Cellular localization: | Endoplasmic reticulum . Golgi apparatus . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. . |
| Background: | This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016], |
| Species Reactivity: | Human;Mouse |
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Western Blot analysis of LOVO cells using Glucosidase IIα Polyclonal Antibody -
Western blot analysis of lysates from LOVO cells, using GANAB Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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