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ELK Biotechnology
SKU:ES5314
Raftlin Rabbit Polyclonal Antibody
Raftlin Rabbit Polyclonal Antibody
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$248.00 USD
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Raftlin Rabbit Polyclonal Antibody
Overview
| Product name: | Raftlin rabbit pAb |
| Alternative Names: | RFTN1; KIAA0084; MIG2; Raftlin; Cell migration-inducing gene 2 protein; Raft-linking protein |
| Applications: | WB;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human RFTN1. AA range:432-481 |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 65kD |
| GeneID(Human): | 23180 |
| Human Swiss-Prot No: | Q14699 |
| Cellular localization: | Cell membrane ; Lipid-anchor . Cytoplasm . Membrane raft . Endosome . Early endosome . Translocates from cytoplasm to cell membrane where it colocalizes with poly (I:C) and then moves to endosomes where it colocalizes with TLR3 (PubMed:21266579). Translocates from cytoplasm to cell membrane where it colocalizes with TLR4 and then together with TLR4 moves to endosomes, upon lipopolysaccharide stimulation (PubMed:27022195). . |
| Background: | function:May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor-mediated signaling.,similarity:Belongs to the raftlin family.,subcellular location:Associates with lipid rafts.,tissue specificity:Specifically expressed by B-cells (at protein level)., |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of 3T3 cells using Raftlin Polyclonal Antibody -
Western blot analysis of RFTN1 Antibody. The lane on the right is blocked with the RFTN1 peptide. -
Western blot analysis of the lysates from RAW264.7cells using RFTN1 antibody. -
Immunohistochemical analysis of paraffin-embedded human uterus. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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