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ELK Biotechnology
SKU:ES5310
NACAD Rabbit Polyclonal Antibody
NACAD Rabbit Polyclonal Antibody
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$248.00 USD
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NACAD Rabbit Polyclonal Antibody
Overview
| Product name: | NACAD rabbit pAb |
| Alternative Names: | NACAD; KIAA0363; NAC-alpha domain-containing protein 1 |
| Applications: | WB;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NACAD. AA range:376-425 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 140kD |
| GeneID(Human): | 23148 |
| Human Swiss-Prot No: | O15069 |
| Cellular localization: | Cytoplasm . Nucleus . |
| Background: | function:May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).,similarity:Belongs to the NAC-alpha family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain., |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of Jurkat cells using NACAD Polyclonal Antibody -
Western blot analysis of lysates from Jurkat cells, using NACAD Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from HeLa cells using NACAD antibody. -
Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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