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ELK Biotechnology

SKU:ES5310

NACAD Rabbit Polyclonal Antibody

NACAD Rabbit Polyclonal Antibody

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NACAD Rabbit Polyclonal Antibody

Overview

Product name: NACAD rabbit pAb
Alternative Names: NACAD; KIAA0363; NAC-alpha domain-containing protein 1
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human NACAD. AA range:376-425
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 140kD
GeneID(Human): 23148
Human Swiss-Prot No: O15069
Cellular localization: Cytoplasm . Nucleus .
Background: function:May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).,similarity:Belongs to the NAC-alpha family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain.,
Species Reactivity: Human;Rat;Mouse;
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